Cancer systems biology is already addressing pressing challenges in the development of new anti-cancer therapies\nand is poised to take an even more leading role in our quest for deeper insights into the biological complexity of cancer. A\npotentially fruitful opportunity for new bioactive marine secondary metabolites lies within the cold water regions of the earth,\nwhere little, but promising, research has been completed in the world wide. Marine sponges have provided a vast resource in\nthe search for bioactive secondary metabolites and potential drug leads. This article discusses about the ADME properties of\nbioactive molecules that have been discovered and the particular significance of a recent sponge possesses medicinal values\nparticularly in various anti-cancer activities including anti-angiogenic, anti-proliferative, topoisomerase inhibition, tubulin\ndisruption and apoptosis inducers followed by antidiabetic, antiinflammatory. Bromotopsentin (94.73) is the highest percentage\nof human oral consumption of compounds and the least value is Lissoclinidine (51.16) among the 24 compounds respectively.
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